3-Pyridazinecarboxylic acid, 1,6-dihydro-6-oxo-, ethyl ester - Names and Identifiers
3-Pyridazinecarboxylic acid, 1,6-dihydro-6-oxo-, ethyl ester - Physico-chemical Properties
Molecular Formula | C7H8N2O3
|
Molar Mass | 168.15 |
Density | 1.33 |
Melting Point | 127-128 °C |
Appearance | Ash powder |
pKa | 10.41±0.40(Predicted) |
Storage Condition | 2-8°C |
3-Pyridazinecarboxylic acid, 1,6-dihydro-6-oxo-, ethyl ester - Introduction
Ethyl 3-pyriridazine-6-carboxylate (Ethyl 3-pyriridazine-6-carboxylate) is an organic compound whose chemical structure contains a pyridazine ring and an ethyl formate group.
Nature:
-Appearance: It is usually colorless to slightly yellow crystal or crystalline powder.
-Solubility: It is soluble in many organic solvents, such as alcohols, ethers and aromatic hydrocarbons, slightly soluble in water.
-Melting point: Its melting point is about 110-112°C.
-Chemical reactivity: It is a medium-strength base that can react with acid to form the corresponding salt. In some organic reactions, it can also participate as an intermediate.
Use:
- Ethyl 3-pyriridazine-6-carboxylate is commonly used as an intermediate in organic synthesis. It can be used to synthesize a series of bioactive compounds, such as pesticides, pharmaceuticals and ligands.
-Because of its special properties in catalyst, homogeneous catalysis and metal complex preparation, it is also used in some catalytic reactions.
Preparation Method:
- Ethyl 3-pyriridazine-6-carboxylate can be prepared by reacting pyridazinone with ethyl formate. The reaction is generally carried out at an appropriate temperature and ratio of reactants, with the aid of a suitable reaction solvent.
-After the reaction is over, the target product can be purified and harvested by solvent distillation or extraction.
Safety Information:
-The specific harmfulness of Ethyl 3-pyriridazine-6-carboxylate has not been reported.
-It is a chemical and should be handled in accordance with personal protection requirements to avoid inhalation, contact with skin and eyes.
Last Update:2024-04-09 21:04:16